Anti-NMDA Receptor Encephalitis presenting with severe episodic hypertension: a case report

Anti-N-methyl-D-aspartate receptor (Anti-NMDAR) encephalitis is one of the most commonly emerging autoimmune in children and young adults recent years. Clinical manifestations range from prodromal symptoms to seizures, movement disorder, psychiatric manifestations, cognitive/speech impairment, autonomic dysfunction. Our case presented with initial severe episodic hypertension, sweating, agitation, tachycardia. She received early care for pheochromocytoma panic disorder Qatar, but there was no relief. Three weeks later, she our emergency room orofacial dyskinesia. Electroencephalography EEG revealed right hemispheric delta activity cerebrospinal fluid CSF anti-NMDA Receptor IgG positive. Magnetic resonance imaging MRI brain studies were normal. treated symptomatically hypertension manifestations. high dosage pulse intravenous methylprednisolone, followed by immunoglobulin, which significantly alleviated her cognitive, neuropsychiatric, features. Severe Hypertension an uncommon presentation Anti- NMDAR encephalitis. Early recognition prompt management improves prognosis long term sequelae.